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What are the odds that the company using an adjuvant that could [theoretically] induce #lupus has also just received FDA approval for a breakthrough lupus treatment?

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" I will just repeat something I've said before. Bookmark this tweet. Hydroxychloroquine will be required long term for people that signed up to investigational RNA therapy. The very same people that denigrated it." Did we all overlook the possible implications of this? @mentions The patent for this "bio-adjuvant" was registered in 2017. Here it is. Any mRNA candidate using this component therefore did not exist before 2017 and could not have been tested in the clinical arena before then. patentscope.wipo.int/search/en/deta… What are the odds that the company using an adjuvant that could [theoretically] induce  #lupus  has also just received FDA approval for a breakthrough lupus treatment? I'm so thankful that these companies can find the solutions to all these problems! According to the inventor Ugur Sahin, the first trials of the RNA vaccine candidates in humans was published in 2017 of 13 patients. The paper doesn't have a comprehensive methods sec...

Transmission in the Vaccinated: Vietnam Hospital Worker Study PREPRINT

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 https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3897733 Abstract Background: Data on breakthrough SARS-CoV-2 Delta variant infections are limited. Methods: We studied breakthrough infections among healthcare workers of a major infectious diseases hospital in Vietnam. We collected demographics, vaccination history and results of PCR diagnosis alongside clinical data. We measured SARS-CoV-2 (neutralizing) antibodies at diagnosis, and at week 1, 2 and 3 after diagnosis. We sequenced the viruses using ARTIC protocol. Findings: Between 11th–25th June 2021 (week 7–8 after dose 2), 69 healthcare workers were tested positive for SARS-CoV-2. 62 participated in the clinical study. 49 were (pre)symptomatic with one requiring oxygen supplementation. All recovered uneventfully. 23 complete-genome sequences were obtained. They all belonged to the Delta variant, and were phylogenetically distinct from the contemporary Delta variant sequences obtained from community transmission cases, sugges...

Leaky Vaccines Create Variants-The Vaccinated Infect the Unvaccinated

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516275/ RESEARCH ARTICLE Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens Andrew F. Read1,2*, Susan J. Baigent3 , Claire Powers3 , Lydia B. Kgosana3 , Luke Blackwell3 , Lorraine P. Smith3 , David A. Kennedy1,2, Stephen W. Walkden-Brown4 , Venugopal K. Nair3 1 Center for Infectious Disease Dynamics, Departments of Biology and Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America, 2 Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America, 3 Avian Oncogenic Virus Group, The Pirbright Institute, Compton, Newbury, Berkshire, United Kingdom, 4 School of Environmental and Rural Science, The University of New England, Armidale, Australia * a.read@psu.edu Abstract Could some vaccines drive the evolution of more virulent pathogens? Conventional wisdom is that natural selection will remove highly lethal pathogens if ho...